Minimum inhibitory concentration-Agar dilution/ E test method

Minimum Inhibitory concentration:

Minimum inhibitory concentration (MIC) is defined as lowest concentration of an antimicrobial agent which inhibits the visible growth of microorganisms, MIC is considered a gold standard for determining the susceptibility of an organism against an antimicrobial agent

Advantages of MIC:

• It is used to confirm unusual resistance pattern
• When borderline results are obtained by disk diffusion method
• When disk diffusion method testing a particular antibiotic against a microorganism may give unreliable results.
• Widely used in antimicrobial resistance surveillance
• Used in comparative testing of new antimicrobial drugs
• Epidemiological studies of susceptibility patterns
• When quantitative results are needed for clinical management of patient

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